By Oliver Sacks
The writer of twelve books, together with the bestselling Awakenings, the fellow Who Mistook His spouse For a Hat, Musicophilia, and Hallucinations, Oliver Sacks is across the world well known for his compassionate method of sufferers stricken by profound neurological issues. but while an twist of fate on an uninhabited mountain in Norway leaves Dr. Sacks with a critical leg harm, he turns into the sufferer. in the course of what must have been a regimen restoration interval, he stories an overpowering sensation that his injured leg is now absent from his physique, and certainly from his actual understanding. In A Leg to face On, one in every of Dr. Sacks’ such a lot own works, this traumatic adventure is the start line of a desirable trip throughout the mysteries of conception, the actual substance of our identities, and the event of being a patient.
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Additional info for A Leg to Stand On
51 Gross features of a benign mixed epithelialstromal tumor Fig. 52 Microscopic features suggest benign lesion 36 Fig. 53 Gross features of mixed epithelial-stromal with malignant transformation Fig. 9 Soft Tissue Tumors 37 Fig. 55 High power view of image Fig. 54 Fig. 1 Medullary Fibroma • Also known as renomedullary interstitial cell tumor. These tumors are frequently multiple and found incidentally at autopsy or surgery for another condition. 5 cm (Fig. 57). • The cells are small stellate, spindle or polygonal in a loose basophilic stroma and seems to originate from prostaglandin-producing interstitial cells in renal medulla.
Metanephric adenoma has a normal karyotype. • Metanephric adenofibroma shows an epithelial component similar to metanephric adenoma which is embedded in a fibroblast-like stroma. • Rare cases of metanephric stromal tumor, entirely composed of stromal elements showing entrapped glomerulus with juxtaglomerular cell hyperplasia have been described. 2 Renal Tumors and Tumor-Like Conditions Renal Oncocytoma Metanephric Tumors • This group includes metanephric adenoma, metanephric adenofibroma and metanephric stromal tumor.
No pathologic feature is predictive of outcome. About 50 % of patients die of their disease. • Hemangioperocytoma may be difficult to distinguish from solitary fibrous tumor owing to their common expression of CD34. 46 1 Renal Tumors and Tumor-Like Conditions • Some authorities consider that cases of hemangiopericytoma in the past should be considered to be solitary fibrous tumor. 18 Hemangioblastoma • Hemangioblastoma is a benign, morphologically distinctive neoplasm that typically occurs in the central nervous system either in the setting of von Hippel-Lindau disease or more often sporadically.